Cambio - Excellence in Molecular Biology

Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

Heat shock protein 27 (Hsp27) (hu)

Heat shock protein 27 (Hsp27) to Human Protein Target

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
ATW0009-100Heat shock protein 27 (Hsp27) (hu) 10 AEU (100ug) POA Quantity Add to Order
ATW0009-25Heat shock protein 27 (Hsp27) (hu) 2.5 AEU (25ug) POA Quantity Add to Order

Description

Heat shock protein 27 (Hsp27) is a chaperone of the sHsp (small heat shock protein) group among ubiquitin, -crystallin, Hsp20 and others. The common functions of sHsps are chaperone activity, thermotolerance, inhibition of apoptosis, regulation of cell development, and cell differentiation. They also take part in signal transduction.

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and Heat Shock Protein 27 (Hsp27), Human Recombinant, Prospec, [cat# HSP-027] as a target and 20 mM Tris, 100 mM NaCl, 0.005% Tween20, in nuclease free water, pH 7.4.  Let us know if you have any questions about it's development or potential uses.

Target:   Hsp27 (Heat Shock Protein 27)

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   70.7 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

Aptamer information Kd 70.7nM

Datasheet

Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Protocols

Datasheet

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

References

Base Pair Biotechnologies Aptamers Combined with Vista Therapeutics NanoBioSensorsTM for Biomarker Measurement in Human Serum

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Notes

Antibody Equivalent Units (AEU). There is a  large molecular weight difference in antibodies (typically 150,000 Da) and Base Pair’s aptamers (~14,000 Da). We provide our aptamers in terms of moles, where the aptamer moles in 1  AEU is equal to antibody moles in the typical 100 microgram shipment from a leading antibody vendor. Therefore our standard 2.5 AEU (25ug) or 5 AEU (50ug) delivery is 2.5 and 5 times the equivalent moles of a standard antibody delivery of 100 microgram respectively.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Related products

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200