Human cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B is a 907-amino acid glycoprotein encoded by the ORF of UL55. It is the most abundant component of the envelope with at least two defined neutralizing epitopes, a target of neutralizing antibodies and an essential replication component. gB plays important roles in HCMV entry, cell-cell spread of internal virions, and fusion of infected cells. It triggers penetration of cells and enhances the spread of infection in nonpolarized human fibroblasts
This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and human CMV gB, [Sino Biological Inc., Cat #10202-V08H1] as a target and 1X PBS, pH 7.4, 1 mM MgCl2.
Target: CMV gB (Cytomegalovirus gB)
Target Species: viral
Target Type: protein
Affinity Constant (Kd): 17.2 nM
Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.
Aptamer information Kd 17.2± 2.1 nM
CMVgB ATW0043 #40 datasheet
Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)
If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200