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Oligo Synthesis

Oligo Synthesis : Reagents, Labelling

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4,5-Dicyanoimidazole (DCI), Crystalline

4,5-Dicyanoimidazole (DCI), Crystalline

Glen Research

Catalogue No.DescriptionPack SizePriceQty
30-3050-104,5-Dicyanoimidazole (DCI), Crystalline 1.0g £32.00 Quantity Add to Order
30-3050-254,5-Dicyanoimidazole (DCI), Crystalline 25.0g £455.00 Quantity Add to Order

Description

4,5-Dicyanoimidazole (DCI), Crystalline

Structure

Catalog Number: 30-3050-xx

Description: 4,5-Dicyanoimidazole (DCI), Crystalline

4,5-Dicyanoimidazole
Formula: C5H2N4 M.W.: 118.1

Diluent: Anhydrous Acetonitrile
Coupling: No changes needeed
Deprotection: No changes needed from standard method recommended by synthesizer manufacturer.
Storage: Controlled room temperature or lower, dry
Stability in Solution:
Please Note: A license may be required from Isis Pharmaceuticals, Inc. to use DCI as an activator in oligonucleotide synthesis as claimed in U.S. Patent Numbers 5,734,041; 6,031,092; 6,160,109 and foreign equivalents.

Catalog Number: 30-3050-xx

Description: 4,5-Dicyanoimidazole (DCI), Crystalline

4,5-Dicyanoimidazole
Formula: C5H2N4 M.W.: 118.1

Diluent: Anhydrous Acetonitrile
Coupling: No changes needeed
Deprotection: No changes needed from standard method recommended by synthesizer manufacturer.
Storage: Controlled room temperature or lower, dry
Stability in Solution:

Please Note: A license may be required from Isis Pharmaceuticals, Inc. to use DCI as an activator in oligonucleotide synthesis as claimed in U.S. Patent Numbers 5,734,041; 6,031,092; 6,160,109 and foreign equivalents.

ALTERNATIVE SOLVENTS/REAGENTS

Glen Research offers alternative solvents and reagents in suitable bottles and formulations for use on various DNA synthesizers. All solvents and reagents are prepared to our exacting specifications to ensure the highest coupling efficiencies and are passed through a 0.2 micron filter during packaging to eliminate particulate contamination. Glen Research offers the activators below in powder form for later dissolution in anhydrous acetonitrile or as a prepared solution.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Protocols

MSDS

Glen Report 10.1: DCI - A LOGICAL ALTERNATIVE ACTIVATOR

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Applications & Benefits

EXTINCTION DATA

Item Nucleoside λMax-1 Emax-1 λMax-2 Emax-2 E260


(nm) (ml/µmole) nm (ml/µmole) (ml/µmole)
30-3050 4,5-Dicyanoimidazole 248 5.94

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Related products

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200