Brain natriuretic peptide, BNP-32, is a 32-amino acid peptide that is
synthisized within the ventricles of the heart. Natriuretiuc peptides
regulate sodium and water balance, blood volume, and arterial pressure.
BNP-32 is a biomarker for heart failure.
Datasheet
Target: BNP (Brain Natriuretic Peptide)
Target Species: human
Target Type: peptide
Affinity Constant (Kd): 60.4 nM
Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.
Aptamer was selected at Base Pair Biotechnologies from a randomized 32-mer DNA library against the target protein. Proprietary methods were then used to select the aptamer.
Aptamer folding instruction before use:
Once the aptamer is in its working concentration, it needs to be heated to 85-95 ºC for 5 minutes, and then cooled to room temperature (~15 minutes) before use.
Validation data by Microscale Thernophoresis (MST) analysis:
Buffer used for validation: 1X PBS, pH = 7.4, 1 mM MgCl2, 0.05% Tween
Average Kd: 60.4 ± 10.9 nM
Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)
Custom aptamers can be developed; contact us for details
If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200