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Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

CD19 Aptamer to Human Protein Target B lymphocyte antigen

CD19 (hu) ATW0016

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
ATW0016-100CD19 (hu) 10 AEU (100ug) POA Quantity Add to Order
ATW0016-25CD19 (hu) 2.5 AEU (25ug) POA Quantity Add to Order

Description

ATW0016 CD19 Aptamer to Human Protein Target B lymphocyte antigen

CD19 also known as CD19 (Cluster of Differentiation 19), is a protein that in humans is found on the surface of B cells, a type of white blood cell. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase.

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and Recombinant CD19 Human Proteins, Sino Biological Inc., [Cat# 11880-H08H] as a target and 1X PBS, pH = 7.4.  Let us know if you have any questions about its development or potential uses.

Target:   CD19

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   51.6 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

Aptamer information: Kd 51.6 ± 13.9 nM

CD19 ATW0016 #701 datasheet

Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)

Custom aptamers can be developed; please contact us for details.

 

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Protocols

CD19 ATW0016 #701 datasheet

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Notes

Antibody Equivalent Units (AEU). There is a large molecular weight difference in antibodies (typically 150,000 Da) and Base Pair’s aptamers (~14,000 Da). We provide our aptamers in terms of moles, where the aptamer moles in 1  AEU is equal to antibody moles in the typical 100 microgram shipment from a leading antibody vendor. Therefore our standard 2.5 AEU (25ug) or 5 AEU (50ug) delivery is 2.5 and 5 times the equivalent moles of a standard antibody delivery of 100 microgram respectively.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Related products

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200