Cambio - Excellence in Molecular Biology

Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

AMACR

Alpha-methylacyl-CoA racemase (AMACR) protein (AMACR) Please remember to pick your Modification from "Related items"

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
ATW0049-100AMACR 10 AEU (100ug) POA Quantity Add to Order
ATW0049-25AMACR 2.5 AEU (25ug) POA Quantity Add to Order

Description

Alpha-Methylacyl-CoA Racemase, AMACR, is an enzyme found in mitochondria and peroxisomes within the cell. It is required for beta oxidation / breakdown of branched-chain fatty acids and bile acid intermediates. AMACR deficiency has been linked to pigmentary retinopathy and adrenomyeloneuropathy. AMACR is overexpressed in prostate cancer.

Target:   AMACR

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   2278 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

Aptamer was selected at Base Pair Biotechnologies from a randomized 32-mer DNA library against target protein. Proprietary methods were then used to select the aptamer.




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Notes

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

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Related products

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200