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Oligo Synthesis

Oligo Synthesis : Supports,CPGs

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3'-Dabsyl CPG

3'-Dabsyl CPG

Glen Research

Catalogue No.DescriptionPack SizePriceQty
20-5911-013'-Dabsyl CPG 0.1g £96.00£88.32Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-5911-103'-Dabsyl CPG 1.0g £780.00£717.60Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-5911-133'-Dabsyl CPG 1x10µm £280.00£257.60Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-5911-143'-Dabsyl CPG 1x15µm £400.00£368.00Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-5911-413'-Dabsyl CPG 4x1.0µm £160.00£147.20Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-5911-423'-Dabsyl CPG 4x0.2µm £96.00£88.32Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order

3'-Dabsyl CPG

3'-Dabsyl CPG

Glen Research

3'-Dabsyl CPG

Structure

Catalog Number: 20-5911-xx

Description: 3'-Dabsyl CPG

1-Dimethoxytrityloxy-3-[O-(N-4'-sulfonyl-4-(dimethylamino)-
azobenzene)-3-aminopropyl]-propyl-2-O-succinoyl-long chain alkylamino-CPG


F.W.: 498.49

Diluent: Not Applicable
Coupling: This support should be used in a manner identical to normal protected nucleoside support since it contains the DMT group.
Deprotection: Cleavage of the oligonucleotide from this support requires 2 hours at room temperature with ammonium hydroxide. Complete the deprotection using the protocol required by the nucleobases.
Storage: Freezer storage, -10 to -30°C, dry
Stability in Solution: Not Applicable

 

Dabcyl LABELLING

A molecular beacon probe1 has its natural fluorescence quenched in solution unless it is hybridized to the target sequence. Consequently, the design of a molecular beacon requires a fluorophore to be in one part of the sequence and the quencher molecule to be in another, with both molecules being separated from the oligonucleotide by a hydrocarbon spacer. The Dabcyl group has been found to be a universal quencher. 3’-Dabsyl CPG and 3’-Dabcyl CPG are used to prepare probes with the quencher blocking the 3’-terminus. 5’-Dabcyl Phosphoramidite locates the quencher at the 5’-terminus and Dabcyl-dT places it within the sequence, leaving the 3’-terminus available for polymerase extension.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

3'-Dabsyl CPG

3'-Dabsyl CPG

Glen Research

MSDS

Glen Report 9.1

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200