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Aptamers

Aptamers: Catalogue Aptamers

Please remember to pick your Modification from "Related items"

All Aptamers from Base Pair Bio are available with the following modifications

Please choose your modification and add as an extra catalogue number:

 

ATWUNMOD - Unmodified

ATWAMINE - Amine modification

ATWBIOTIN - Biotin modification

ATWTHIOL - Thiol modification (extra charge)

ATWFLUOR - Fluor (all) modification (extra charge)

 

Zika aptamer ATW0104

This Zika aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and Zika envelope protein from ProSpec as a target.

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
ATW0104-100ATW0104 Zika Aptamer10 AEU (100ug) POA Quantity Add to Order
ATW0104-25ATW0104 Zika Aptamer2.5 AEU (25ug) POA Quantity Add to Order

Zika aptamer ATW0104

This Zika aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and Zika envelope protein from ProSpec as a target.

Base Pair Bio

Zika virus is a mosquito-borne flavivirus. It is transmitted by the Aedes mosquito, which also transmits Dengue, Chikungunya, and yellow fever. Contraction of Zika during pregnancy can cause microcephaly and other abnormalities in newborns as well as fetal loss, stillbirth, and pre-term birth. Zika infection has also been linked to Guillain-Barre syndrome, neuropathy, and myelitis (1). This DNA aptamer was selected against the Zika envelope protein in mosquito saliva, but has also been shown to bind the Zika envelope protein in serum and defibrinated blood (2).

  1. WHO. https://www.who.int/news-room/fact-sheets/detail/zika-virus. Accessed May 15, 2019.
  2. Saraf, N., et al. Multiplex viral detection platform based on a aptamers-integrated microfluidic channel. ACS Omega. 2019. 4:2234-2240.

Target:   Zika

Target Species:   viral

Target Type:   protein

Affinity Constant (Kd):   2.2 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

Zika aptamer ATW0104

This Zika aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and Zika envelope protein from ProSpec as a target.

Base Pair Bio

Download from Base Pair's website here https://www.basepairbio.com/store/atw0104-zika-aptamer/

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

Zika aptamer ATW0104

This Zika aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and Zika envelope protein from ProSpec as a target.

Base Pair Bio

1. WHO. https://www.who.int/news-room/fact-sheets/detail/zika-virus. Accessed May 15, 2019. 2. Saraf, N., et al. Multiplex viral detection platform based on a aptamers-integrated microfluidic channel. ACS Omega. 2019. 4:2234-2240.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

Zika aptamer ATW0104

This Zika aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and Zika envelope protein from ProSpec as a target.

Base Pair Bio

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200