
Easy and scalable enzymatic double-stranded RNA (dsRNA) removal from IVT RNA samples.
Reduces sample dsRNA to <0.005% (LLOQ) to minimize immunogenicity in cells.
Circumvents the need for chromatographic methods like HPLC.
Retains single-stranded RNA (ssRNA) yields.
Combine with modified nucleoside transcription for maximum reduction of immunogenicity.