Cambio - Excellence in Molecular Biology

In Vitro Toxicology

In Vitro Toxicology: Mutagenicity kits

The Ames II / Ames MPF Microfluctuation Assays are all modifications of the traditional Ames plate incorporation assay.

The Ames II assay uses the S. typhimurium strains TA98 and TAMix (a mixture of 6 strains, each detecting a specific base-pair substitution), whereas the Ames MPF® kits are available with the strains TA98, TA100, TA1535, TA1537, E.coli WP2 uvrA or E.coli WP2 pKM101.


Benefits of Xenometrix Ames Mutagenicity Assays over traditional Ames Procedures

  • Easy, compact and high throughput liquid format with 384 well plates.

  • Simple detection method with easy "readout" (as compared to the traditional assay)

  • Kits include all five types strains cited in OECD 471 (CoA supplied), quality controlled according to the same guideline 

  • Much less  test compound required.  (10 mg per strain if tested in triplicates, +/- S9, 6 semi-logarithmic compound dilutions)

  • Ames MPF is the preferred system for genotoxic impurities due to its low consumption of compound

  • Significantly less consumption of S9

  • Less environmental pollution due to significantly less "contaminated" waste

  • Less user intervention

  • Download presentation 

Sterile Ames Plates filters and caps

Sterile plates, filters and caps to be used in Ames testing

Xenometrix AG

Catalogue No.DescriptionPack SizePriceQty
XPPW-0120Sterile 25 well square plates120 Plates / Box £591.00 Quantity Add to Order
XPPW-0725Sterile 24-well exposure plates1 pack (of 126) £335.00 Quantity Add to Order
XPPW-0924Sterile 384-well plates1 pack ( of 36 ) £239.00 Quantity Add to Order
XPPW-8100Sterile 96 well chemical plate1 Pack (160 plates) £381.00 Quantity Add to Order


Sterile plates, tubes and caps for use with Ames Test kit.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200