ATW0092 Aptamer to Phosphorylated ERK1 Thr202 (aa 190-208) Peptide
ERK1 (Mitogen-activated protein kinase 3, also known as ERK1) is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases.
This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and phosphorylated aa202 ERK1 (aa 190-208) peptide CIADPEHDHTGFL(t)EYVATR as a target and 1X PBS, 1mM MgCl2, 0.02% Tween, 20% Human Serum. Let us know if you have any questions about its development or potential uses.
***This aptamer does not bind non phosphorylated ERK1 (aa 190-208) CIADPEHDHTGFLTEYVATR***
Target: ERK1 (aa190-208) Phospho aa202
Target Species: multi-species
Target Type: peptide
Dissociation Constant (Kd): 12.9 nM
Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.
*Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.
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