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Aptamers

Aptamers: Catalogue Aptamers

Important information

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Citrulline Aptamer

Citrulline Aptamer

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
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ATW0100-100Citrulline Aptamer10 AEU (100ug) POA Quantity Add to Order
ATW0100-25Citrulline Aptamer2.5 AEU (25ug) POA Quantity Add to Order

Description

Citrulline (CIT) is an amino acid involved in arginine (ARG) metabolism. It is named after the watermelon, Citrullis Vulgaris, from which it was first discovered. Citrulline binds the hydroxyl radical, protecting DNA and metabolic enzymes from oxidation. It is involved in nitrogen balance and muscle homeostasis. Citrulline can stimulate muscle protein synthesis and has become a popular nutritional supplement. Circulating citrulline is elevated in renal failure and decreased in intestinal failure (1).

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and L-Citrulline [Sigma, Cat# C7629] as a target.

Target:   Citrulline

Target Species:   N/A

Target Type:   Amino Acid

Affinity Constant (Kd):   4961nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

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References

Christophe Moinard and Luc Cynobar. Citrulline: A new player in the control of nitrogen homeostasis. J. Nutr. 2007. 137:1621S-1625S.

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Notes

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

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