DEHP, or Di(2-ethylhexyl) phthalate (DEHP) is a chemical
added to plastics, including PVC/vinyl to increase flexibility. It can be found
in many household products, including wallpaper, shower curtains, swimming pool
liners, plastic lunch boxes, and some plastic food packaging. It is also found
in certain medical devices, including dialysis tubing, surgical gloves and
blood storage bags. It is currently regulated in children’s toys and clothing.
Exposure to high doses and extended exposure have caused liver/kidney damage
and liver tumors and affected reproductive development in animal studies. The
EPA has designated DEHP a probable carcinogen. Exposure to newborns or pregnant women is of
particular concern. DEHP can gradually be released from products and accumulate
in the home and environment. The greatest risks are ingestion through
contaminated food or water and extended exposure through medical devices.
Target: DEHP
Target Type: compound
Affinity Constant (Kd): 16.6 nM
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