Description
Ames II is a
miniaturized, ready to use Ames Test kit in a liquid microplate format.
It includes all reagents necessary to run 10 samples with strains TA98
and TAMix (Mix of TA7001, TA7002, TA7003, TA7004, TA7005, TA7006): 10
vials each of frozen TA98, TAMix, plus Growth -, Exposure -, Reversion
Indicator Media, Ampicillin, Positive Controls, lyophilized
Post-Mitochondrial Supernatant S9 from Aroclor 1254 induced rat liver.
Not included in the kit are plastic ware and S9 Cofactor solutions.
The kits are quality controlled and do not need an inhouse quality control (phenotypes) like the traditional agar plate assay.
Service analytics for early drug discovery with test compound of
11 mg / strain ( /- S9) with the Ames MII or Ames MPF assay system is
available as well under GLP and non GLP conditions, please contact info@xenometrix.ch.
Characteristics
- Quality controlled products: all products of the kit
- Certificate of Analysis: Provided
- Excel Calculation Sheet to support Data Interpretation
- Comparison with agar late test: Corresponds to 2 x 480 agar plates.
- Enough Material to process Strains individually
- Shipped on dry ice from external Storage in Germany
- High sensitivity and excellent correlation with agar plate test (see database and publications on this homepage)
- 4 times less test compound as compared to the agar plate test
- Less hands-on-time and simultaneous processing of several replicates
- Automation available - High throughput format
- 3Rs - 12 fold less consumption of rat liver liver S9, less test animals
- Less error prone due to easy colorimetric read-out
- Waste - Significant less plastic waste and thus reduced contaminated waste in environment
Also available
- S9 Cofactor Kit (Art.No. PCO-0800) for preparation of S9 Mix
- A10-210-S1-P Ames MPF 98/100 with S9 induced by Aroclor 1254 - shipped at RT
- A10-210-S2-P Ames 98/100 with S9 induced by PB/ß-Naphtoflavone induced rat liver S9* - shipped at RT
- Ames MPF 98/100 Aqua for environmental water samples - shipped at RT
- Ready to use 5 Strain kits Ames MPF Penta 1 and Penta 2 - shipped at RT
- Individual Reagents, such as rat liver S9
*strongly recommended over Aroclor induced S9, Aroclor being a strong
environmental polutant and on the EC list of banned chemicals.
Short Protocol
Leaflets
Stability studies
MSDS
If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200