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Oligo Synthesis

Oligo Synthesis : Supports, CPGs

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3'-DBCO-Serinol CPG

Dibenzo-cyclooctyne (DBCO) enables copper-free click chemistry, and our 3'-DBCO-Serinol CPG allows customers to place a DBCO modification at the 3'-end of their oligo...

Glen Research

Catalogue No.DescriptionPack SizePriceQty
20-2998-013'-DBCO-Serinol CPG0.1g £83.00 Quantity Add to Order
20-2998-103'-DBCO-Serinol CPG1.0g £679.00 Quantity Add to Order
20-2998-133'-DBCO-Serinol CPG1x 10 umol £233.00 Quantity Add to Order
20-2998-143'-DBCO-Serinol CPG1x 15 umol £346.00 Quantity Add to Order
20-2998-413'-DBCO-Serinol CPG4x 0.1 umol £125.00 Quantity Add to Order
20-2998-423'-DBCO-Serinol CPG4x 0.2 umol £75.00 Quantity Add to Order

Description

Description

3-Dimethoxytrityloxy-2-(6-oxo-6-(dibenzo[b,f]azacyclooct-4-yn-1-yl)-capramido)propyl-1-O-succinyl-long chain alkylamino-CPG

Dibenzo-cyclooctyne (DBCO) enables copper-free click chemistry, and our 3'-D

BCO-Serinol CPG allows customers to place a DBCO modification at the 3'-end of their oligo without the use of a universal support. We recommend using 0.5M CSO oxidizer to prevent loss of DBCO label when using standard iodine oxidation.

 

Details

Usage

  • Coupling: DBCO Serinol is susceptible to damage by iodine during oxidation. To prevent loss of the DBCO label, use 0.5M CSO in anhydrous acetonitrile (40-4632-xx) and a 3 minute oxidation time for best results.
  • Deprotection: Ammonium hydroxide for 2 hr at 65°C or as required by nucleobases.
Specifications
Storage Freezer storage, -10 to -30°C, dry

Product Specifications

F.W.:468.45
Pore Size:1000Å


Technical Documents

Safety Data Sheet (EU)

Safety Data Sheet (Other)

Glen Report 36-24: New Products Catalyst-free Click Reactions

 

 

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