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Oligo Synthesis

Oligo Synthesis : Supports, CPGs

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3'-Amino-Modifier Serinol CPG

3'-Amino-Modifier Serinol CPG

Glen Research

Catalogue No.DescriptionPack SizePriceQty
20-2997-013'-Amino-Modifier Serinol CPG 0.1g £86.00 Quantity Add to Order
20-2997-103'-Amino-Modifier Serinol CPG 1.0g £614.00 Quantity Add to Order
20-2997-133'-Amino-Modifier Serinol CPG 1x10µm £227.00 Quantity Add to Order
20-2997-143'-Amino-Modifier Serinol CPG 1x15µm £341.00 Quantity Add to Order
20-2997-413'-Amino-Modifier Serinol CPG 4x1.0µm £127.00 Quantity Add to Order
20-2997-423'-Amino-Modifier Serinol CPG 4x0.2µm £77.00 Quantity Add to Order

Description

3'-Amino-Modifier Serinol CPG

Structure

Catalog Number: 20-2997-xx

Description: 3'-Amino-Modifier Serinol CPG

3-Dimethoxytrityloxy-2-(3-(fluorenylmethoxycarbonylamino)propanamido)propyl-1-O-
succinyl-long chain alkylamino-CPG


F.W.: 224.15

Diluent: n/a
Coupling: No changes needed from standard method recommended by synthesizer manufacturer.
Deprotection: Deprotect using the protocol required by the nucleobases.
Storage: Refrigerated storage, maximum of 2-8°C, dry
Stability in Solution: Not Applicable

’-MODIFIERS

3’-Amino-Modifier CPGs, containing amino groups protected with the base-labile Fmoc group, are designed to functionalize the 3’-terminus of the target oligonucleotide by the introduction of a primary amine. In an alternative approach, the nitrogen destined to become the 3’-amino group is included in a phthalimide (PT) group which is attached to the support through an amide group attached to the aromatic ring. This simple linkage is very stable to all conditions of oligonucleotide synthesis and contains no chiral center. Using an extended ammonium hydroxide treatment (55°C for 17 hours), the cleavage of the amine from the phthalimide is accomplished along with the deprotection of the oligonucleotide. ABI-style columns are supplied unless otherwise requested.

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Protocols

MSDS

Glen Report

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Related products

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