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Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

Aptamer to the Small Molecule Target Epirubicin

Small Molecule Target Epirubicin aptamer

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
ATW0006-100Epirubicin 10 AEU (100ug) POA Quantity Add to Order
ATW0006-25Epirubicin 2.5 AEU (25ug) POA Quantity Add to Order

Description

Epirubicin is an anthracycline drug used for chemotherapy. It can be used in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. It is marketed by Pfizer under the trade name Ellence in the US and Pharmorubicin or Epirubicin Ebewe elsewhere.

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and epirubicin as a target and 20 mM Tris, 100 mM NaCl, 0.005% Tween20 in nuclease free water, pH 7.4. Let us know if you have any questions about its development or potential uses.

Epirubicin

DataSheet

Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)

Target:   Epirubicin

Target Species:   N/A

Target Type:   small molecule

Affinity Constant (Kd):   711 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.



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Protocols

DataSheet

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Notes

Antibody Equivalent Units (AEU).  There is a  large molecular weight difference in antibodies (typically 150,000 Da) and Base Pair’s aptamers (~14,000 Da).   We provide our aptamers in terms of moles, where the aptamer moles in 1  AEU is equal to antibody moles in the typical 100 microgram shipment from a leading antibody vendor. Therefore our standard 2.5 AEU (25ug) or 5 AEU (50ug) delivery is 2.5 and 5 times the equivalent moles of a standard antibody delivery of 100 microgram respectively

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Technical Help

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Related products

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