Interferon gamma (IFNγ)is a dimerized soluble cytokine that is the only member of the type II class of interferons and is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNγ is an important activator of macrophages. Aberrant IFNγ expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFNγ in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects.
Target: IFN Gamma
Target Species: bovine
Target Type: protein
Affinity Constant (Kd): 33.7 nM
Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.
This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and Bovine IFNγ [GenWay Biotech Inc. Cat. #GWB-0F0115] as a target and 1X PBS, pH 7.4, 1 mM MgCl2. Let us know if you have any questions about its development or potential uses.
Aptamer information Kd 33.7 ± 6.0 nM
Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)
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