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Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

Dengue Type 2 NS1 Aptamer

Dengue Type 2 NS1 Aptamer to Viral Protein Target ATW0004

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
ATW0004-100Dengue NS1 protein 10 AEU (100ug) POA Quantity Add to Order
ATW0004-25Dengue NS1 protein 2.5 AEU (25ug) POA Quantity Add to Order

Description

Dengue virus is the cause of dengue fever. It is a mosquito-borne single positive-stranded RNA virus. There are four antigenically related, but distinct, dengue virus serotypes (DEN-1, DEN-2, DEN-3 and DEN-4) and DEN-2 nonstructural protein-1 (NS1) is a secreted glycoprotein that is absent from viral particles but accumulates in the supernatant and on the plasma membrane of cells during infection.

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods, a provided target of non reported origin and 1X PBS pH 7.4.  Let us know if you have any questions about its development or potential uses.

Target:   Dengue Type 2 NS1

Target Species:   viral

Target Type:   protein

Affinity Constant (Kd):   21 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

Aptamer information Kd 21nM

Dengue Type 2 NSI ATW0004 #534 datasheet

Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Protocols

Dengue Type 2 NSI ATW0004 #534 datasheet

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Notes

Antibody Equivalent Units (AEU). There is a  large molecular weight difference in antibodies (typically 150,000 Da) and Base Pair’s aptamers (~14,000 Da). We provide our aptamers in terms of moles, where the aptamer moles in 1  AEU is equal to antibody moles in the typical 100 microgram shipment from a leading antibody vendor. Therefore our standard 2.5 AEU (25ug) or 5 AEU (50ug) delivery is 2.5 and 5 times the equivalent moles of a standard antibody delivery of 100 microgram respectively.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Related products

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200