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Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

Cytokeratin 19 (hu)

Cytokeratin 19 (hu) ATW0053

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
ATW0053-100Cytokeratin 19 (hu) 10 AEU (100ug) POA Quantity Add to Order
ATW0053-25Cytokeratin 19 (hu) 2.5 AEU (25ug) POA Quantity Add to Order

Description

Cyokeratin 19 is a key cytoskeletal protein in endothelial cells. CK19 is released by colorectal and breast cancer cells. The presence of CK19-releasing cells has been correlated with metastasis.

Target:   Cytokeratin 19 (CK-19)

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   63.7 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

Datasheet

(hu) 0.1uM synthesis scale (20-200ug)
Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)

 

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Protocols

Datasheet

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References

Alix-Panabieres, C. et al. (2009) Full-length cytokeratin 19 is released by human tumor cells: a potential role in metastatic progression of breast cancer. Breast Cancer Research. 11:R39. Doi:10.1186/bcr2326

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Notes

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

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Related products

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