| 4-Thio-U-TOM-CE Phosphoramidite |
Catalog Number: 10-3052-xx
Description: 4-Thio-U-TOM-CE Phosphoramidite
5'-Dimethoxytrityl-4-(2-cyanoethylthio)-Uridine,2'-O-triisopropylsilyloxymethyl-
3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite |
| Formula: C52H72N5O9PSSi |
M.W.: 1002.29 |
F.W.: 322.22 |
MINOR RNA PHOSPHORAMIDITES (TOM PROTECTED)
Glen Research offers minor RNA phosphoramidites with either TOM or TBDMS protecting groups. 4-Thio-U, 5-Methyl-Cytidine, 2-Aminopurine riboside and 2-Amino-Adenosine are useful for analyzing RNA structure and activity relationships, for example, in ribozyme studies.
Pyrrolo-C is a fluorescent nucleoside whose fluorescence is sensitive to its environment and is ideal for probing RNA structure. It base-pairs as a normal C nucleotide. It is highly fluorescent and its excitation and emission are well to the red of most fluorescent nucleotide analogs, which eliminates or reduces background fluorescence from proteins. Pyrrolo-CTP has potential uses in biological assay development.
rSpacer is used to introduce an abasic site to an RNA sequence.
The protecting scheme for 2,6-Diaminopurine has been changed and the original product (10-3084) has been replaced with the optimized product (10-3085) below.
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