CD45, also called lymphocyte common antigen, is a membrane glycoprotein. The intracellular region has protein tyrosine phosphatase activity. CD45 is involved in hematopoietic cell differentiation and T cell activation.

Target:   CD45 (protein tyrosine phosphatase)

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   9.7 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

Aptamer was selected at Base Pair Biotechnologies from a randomized 32-mer DNA library against the target protein. Proprietary methods were then used to select the aptamer.

DataSheet

Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

DataSheet

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Altin, J.G., et al. (1997) The role of CD45 and CD45-associated molecules in T cell activation. Immunol. Cell. Biol. 75(5):430-45. and Nakano, A. et al. (1990) Expression of leukocyte common antigen (CD45) on various human leukemia/lymphoma cell lines. Acta. Pathol. Jpn. 40(2):107-15.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

• View3' or 5' Amine Modification
• View3' or 5' Thiol modification
• View3'-Biotin modification
• View5'-FITC modification
• ViewUnmodified