Products for DNA and RNA Synthesis

Welcome to the Oligo Synthesis section. This section contains the Glen Research Catalogue, the most complete selection of products for DNA and RNA research.

Glen Research, part of Maravai LifeSciences, is a leading provider of reagents for DNA and RNA oligonucleotide synthesis, labelling, and modification. Known for its proprietary Sterling™ line of reagents marked with its Sterling Seal of Quality Assurance, Glen analyses and certifies these reagents for purity and performance ensuring consistent, dependable and reliable results. Glen also specializes in oligonucleotide purification supplies under the Glen-Pak™ and Glen Gel-Pak™ product lines.

Some key points for ordering

All minor bases, modifiers and RNA products are packaged for Applied Biosystems instruments. We can provide vials and columns for a wide variety of other instruments. As shown in the table below, we can accommodate catalog numbers for unusual products to fit all popular instruments, or you can use the Packaging Selection guide (pdf).

All minor bases, RNA products and modifiers are packaged in septum-capped vials suitable for ABI and other instruments. If you would like another type of vial/column add the following to the end of the catalog number.

For example, if you wish to order 0.25g of dI-CE Phosphoramidite for an Applied Biosystems instrument, the catalog number is 10-1040-02. If you wish the same product for an Expedite instrument, the catalog number, derived from the table above would be 10-1040-02E. For columns, a pack of four dI columns for an Expedite would be 20-2190-42E. The table to the left is reproduced on all relevant spreads of this catalog.

Why Glen Research?

Glen Research are unique in conducting QC tests for supports, to show the length of an oligo that can be prepared before a drop-off in coupling due to steric effects begins to occur. The drop-off point is recorded in the Certificate of Analysis or Analytical Report. The vast majority of our minor base and modification supports are 1000Å CPG, which results in improved performance and the ability to make much longer oligos. Supports which will continue with a specific pore size are shown as such in the catalogue. Polystyrene supports are also available for some of our most popular items.

For reasons of quality assurance, Glen Research do not transfer powders or oils from stock Applied Biosystems vials to vials for other instruments. Powders may be hygroscopic and electrostatic, making transfer difficult, and oils have to be dissolved and the solvent evaporated. For best performance, it is preferable for the customer to dissolve the product and immediately transfer the solution to the correct instrument vial. Consequently, the product will be delivered in an industry-standard septum-capped vial along with a clean dry vial for the appropriate instrument. We monitor product usage for each instrument type and will attempt to have stock prepackaged for some of the most popular products and configurations.

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