Description
3-Dimethoxytrityloxy-2-(3-palmitamidopropanamido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite
Palmitate Serinol Phosphoramidite
structure features a saturated fatty acid with a 16-carbon chain. When
incorporated into synthetic oligonucleotides, palmitate enhances
cellular uptake and activity in various tissues. The Serinol linker
allows for the incorporation of modifications at the 3′-end, internally,
and at the 5′-end during oligonucleotide synthesis.
Product Specifications
Details
Usage
- Coupling: 6 minute coupling time recommended
- Deprotection: No changes needed from standard method recommended by synthesizer
manufacturer.
| Specifications |
| Diluent |
Anhydrous Acetonitrile |
| Storage |
Freezer storage, -10 to -30°C, dry |
| Stability |
1-2 Days |
Intellectual Property
Serinol products are covered by US Patent No.: 8,394,948.
Dilution/Coupling Data
The table below show pack size data and, for solutions, dilution and approximate coupling based on normal priming procedures.
ABI 392/394
Technical Documents
Safety Data Sheet (EU)
Safety Data Sheet (Other)
Glen Report 36-25: New Product Palmitate Serinol Phosphoramidite
If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200