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Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

IgM mu chain (non-glycated) (hu plasma)

Aptamer to Human IgM mu Chain Plasma Protein

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
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ATW0021-100IgM mu chain (non-glycated) (hu plasma) 10 AEU (100ug) POA Quantity Add to Order
ATW0021-25IgM mu chain (non-glycated) (hu plasma) 2.5 AEU (25ug) POA Quantity Add to Order

Description

Immunoglobulin M, or IgM for short, is a basic antibody that is produced by B cells. IgM is by far the physically largest antibody in the human circulatory system. It is the first antibody to appear in response to initial exposure to antigen. Immunoglobulins are made up of two heavy and two light chains and heavy chains define the isotype.

Amino acid sequence determines the type of heavy chain, Immunoglobulin G has gamma heavy chains and IgM has mu heavy chains.IgM forms polymers where multiple immunoglobulins are covalently linked together with disulfide bonds, mostly as a pentamer but also as a hexamer.

Target:   IgM (Immunoglobulin M)

Target Species:   human

Target Type:   antibody

Affinity Constant (Kd):   178 pM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and IgM mu chain plasma protein, [Athens Research Cat# 16-16-090713-MU]

Datasheet

Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Protocols

Datasheet

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Notes

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200