8-Br-dA-CE Phosphoramidite |
Catalog Number: 10-1007-xx
Description: 8-Br-dA-CE Phosphoramidite
5'-Dimethoxytrityl-N6-dimethylaminomethylidene-8-bromo-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite |
Formula: C43H52N8O6PBr |
M.W.: 887.81 |
F.W.: 392.11 |
Diluent: Anhydrous Acetonitrile |
Coupling: No changes needed from standard method recommended by synthesizer manufacturer. |
Deprotection: Mild Deprotection: Ammonium hydroxide for 24hours at room temperature. |
Storage: Refrigerated storage, maximum of 2-8°C, dry |
Stability in Solution: 24 hours |
HALOGENATED NUCLEOSIDES
Brominated and iodinated nucleosides are used in crystallography studies of oligonucleotide structure. They are also photolabile and are used for cross-linking studies to probe the structure of protein-DNA complexes. Antibodies exist to Br-dU and oligonucleotides containing Br-dU can be used as probes.
If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200