treptococcus pneumoniae microarray probe set covers both genes and intergenic regions of two S. pneumoniae stains: R6 and TIGR4. The design of these microarray probes maximizes the efficiency of probe representation over the homologous regions between the two genomes by utilizing a heuristic search algorithm for design of common oligo probes. Of the 2,879 microarray probes in the set 2,108 cover genes and intergenic regions identical in both genomes. Strain-specific oligos (314 from strain R6, 454 from strain TIGR4) can be used to establish identity of the sample strain.
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