Catalog Number: 10-3000-xx
Description: Pac-A-CE Phosphoramidite
5'-Dimethoxytrityl-N-phenoxyacetyl-Adenosine,2'-O-TBDMS-3'- [(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite |
Formula: C54H68N7O9PSi |
M.W.: 1018.23 |
F.W.: 329.21 |
Diluent: Anhydrous Acetonitrile |
Coupling: 12 minutes. To avoid any exchange of the iPr-Pac group on the G with acetyl, use the UltraMild Cap Mix A (40-4210-xx/ 40-4212-xx). |
Deprotection: RNA Deprotection-see bulletin Technical Bulletin |
Storage: Freezer storage, -10 to -30°C, dry |
Stability in Solution: 24 hours |
TBDMS-PROTECTED RNA PHOSPHORAMIDITES
Glen Research CE (ß-cyanoethyl) Phosphoramidites for RNA synthesis are produced and packaged to ensure the highest performance on commercial synthesizers. Every batch is accompanied by a Certificate of Analysis and an HPLC trace, showing the results of our QC testing. RNA Phosphoramidites are synthesis-tested with a minimum coupling efficiency of 97%. Glen Research RNA monomers are packaged in industry standard vials which are specially cleaned to eliminate particulate contamination. These monomers are available in a variety of packs, including high throughput (HT) and low cost (LC). An UltraMild set is also available for situations where sensitive bases are in use. Dmf-G (10-3029) has been discontinued and may be substituted with Ac-G (10-3025).
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