Immunoglobulin M, or IgM for short,
is a basic antibody that is produced by B cells. IgM is by far the
physically largest antibody in the human circulatory system. It is the
first antibody to appear in response to initial exposure to antigen.
Immunoglobulins are made up of two heavy and two light chains and heavy
chains define the isotype.
Amino acid sequence determines the type of
heavy chain, Immunoglobulin G has gamma heavy chains and IgM has mu
heavy chains.IgM forms polymers where multiple immunoglobulins are
covalently linked together with disulfide bonds, mostly as a pentamer
but also as a hexamer.
Target: IgM (Immunoglobulin M)
Target Species: human
Target Type: antibody
Affinity Constant (Kd): 178 pM
Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.
This aptamer was selected by scientists at
Base Pair Biotechnologies using proprietary methods and IgM mu chain
plasma protein, [Athens Research Cat# 16-16-090713-MU]
Datasheet
Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)
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