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Oligo Synthesis

Oligo Synthesis : Supports,CPGs

Prices quoted are for single packs only.

For multiples of the same product please request a quote.

Some of Glen's products are hazardous and may be subject to additional shipping charges.

Full product information is available on Glen Research's web site.

US III 1500Å HybridCPG

US III 1500Å HybridCPG

Glen Research

Catalogue No.DescriptionPack SizePriceQty
28-5010-01US III 1500Å HybridCPG0.1g £12.80£11.78Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
28-5010-02US III 1500Å HybridCPG0.25g £28.00£25.76Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
28-5010-10US III 1500Å HybridCPG1.0g £100.00£92.00Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order

US III 1500Å HybridCPG

US III 1500Å HybridCPG

Glen Research

 US III 1500Å HybridCPG

Structure

Catalog Number: 28-5010-xx

Description: US III 1500Å HybridCPG






Diluent: Not Applicable
Coupling: This support should be used in a manner identical to normal protected nucleoside support since it contains the DMT group.
Deprotection: See Technical Bulletin for details (Technical Bulletin). Note: This product is not compatible with cyanoethyl protecting group removal protocols using hindered bases such as DEA or DBU. Removal of the cyanoethyl groups prior to cleavage will prevent the release of the oligonucleotide from the support.
Storage: Refrigerated storage, maximum of 2-8°C, dry
Stability in Solution: Not Applicable
Please Note: This product is covered by US Patent No.: 6,770,754.

GLEN UNYSUPPORT

Our original Universal Support (20-5000) has been discontinued since complete dephosphorylation using ammonium hydroxide, AMA and anhydrous methylamine gas takes longer than most companies wish to allocate. A recent development has been the use of a support based on a molecule which is “conformationally preorganized” to accelerate the dephosphorylation reaction.1,2 By using a rigid bicyclic molecule on the support, it was hoped that the molecule’s conformation would facilitate the formation of the cyclic phosphate transition state, thereby stimulating the rate of dephosphorylation. It was found that the rate of elimination is markedly faster than the original Universal Support.

The structure of Glen UnySupport is shown below. The N-phenyl version, developed at Isis Pharmaceuticals as UnyLinker™, is available from several companies for large scale oligo synthesis. Glen UnySupport is the N-methyl version, which is preferred for high throughput oligonucleotide synthesis since methylamine rather than aniline is formed on deprotection. We are happy to offer Glen UnySupport in a variety of popular formats under license from Isis Pharmaceuticals.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

US III 1500Å HybridCPG

US III 1500Å HybridCPG

Glen Research

Material Safety Data Sheet

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200