ATW0013 Aptamer to Human Protein Target, CD19
Datasheet
B lymphocyte antigen CD19 also known as CD19 (Cluster of Differentiation 19), is a protein that in humans is found on the surface of B cells, a type of white blood cell. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase.
This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and Recombinant CD19 Human Proteins, [Sino Biological Inc., Cat# 11880-H08H] as a target and 1X PBS, pH = 7.4. Let us know if you have any questions about its development or potential uses.
Target: CD19
Target Species: human
Target Type: protein
Affinity Constant (Kd): 6.9 nM
Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.
Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)
Custom aptamers can be developed; please contact us for details.
If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200