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Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

CA125/MUC16 (hu)

Recombinant Human CA125/MUC16

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
ATW0055-100CA125/MUC16 (hu) 10 AEU (100ug) POA Quantity Add to Order
ATW0055-25CA125/MUC16 (hu) 2.5 AEU (25ug) POA Quantity Add to Order

Description

Cancer antigen 125 is a glycoprotein expressed in coelomic epithelial tissues, including the ovaries, kidney, and stomach. Elevated CA 125 levels are linked to many types of cancer and other conditions. CA-125 is elevated in ~80% of cases involving advanced epithelial ovarian cancer. CA 125 measurement is currently used for diagnostic and prognostic testing.

Aptamer was selected at Base Pair from a randomized 32-mer DNA library against the target protein protein. Proprietary methods were then used to select the aptamer.

Target:   CA-125 (cancer antigen 125)

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   18.4 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

DataSheet

0.1uM synthesis scale (20-200ug)
Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)

 

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Protocols

DataSheet

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Notes

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

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Related products

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