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Oligo Synthesis

Oligo Synthesis : CEPs

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Serinol-CE Phosphoramidite

3-Dimethoxytrityloxy-2-(adenine-1-acetamido)propyl- 1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite 3-Dimethoxytrityloxy-2-(cytosine-1-acetamido)propyl- 1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite 3-Dimethoxytrityloxy-2-(guanine-1-acetamido)propyl- 1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite 3-Dimethoxytrityloxy-2-(thymine-1-acetamido)propyl- 1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite

Glen Research

Catalogue No.DescriptionPack SizePriceQty
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10-2390-02A-Serinol-CE Phosphoramidite0.25grams €182.90 Quantity Add to Order
10-2390-05A-Serinol-CE Phosphoramidite0.5grams €343.38 Quantity Add to Order
10-2391-02C-Serinol-CE Phosphoramidite0.25grams €182.90 Quantity Add to Order
10-2391-05C-Serinol-CE Phosphoramidite0.5grams €343.38 Quantity Add to Order
10-2392-02G-Serinol-CE Phosphoramidite0.25grams €182.90 Quantity Add to Order
10-2392-05G-Serinol-CE Phosphoramidite0.5grams €343.38 Quantity Add to Order
10-2393-02T-Serinol-CE Phosphoramidite0.25grams €182.90 Quantity Add to Order
10-2393-05T-Serinol-CE Phosphoramidite0.5grams €343.38 Quantity Add to Order

Description

Serinol nucleic acid (SNA) is an acyclic phosphodiester backbone based on serinol (2-amino-1,3-propanediol). It shares the same three carbon skeleton as ribose and has nucleobases that are one atom further away from the skeleton than standard nucleic acids. SNA hybridizes to both DNA and RNA.

 

 

Specifications
Diluent     Anhydrous Acetonitrile
Storage     Freezer storage, -10 to -30°C, dry
Stability     1-2 Days

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References

Glen Report 36 May 2024

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Applications & Benefits

Usage

Coupling: No changes needed from standard method recommended by synthesizer manufacturer.

Deprotection: Ammonium Hydroxide for 4-8 hours at 55 °C.

 

 

 

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200