ERK1 (Mitogen-activated protein kinase 3, also known
as ERK1) is a member of the MAP kinase family. MAP kinases, also known
as extracellular signal-regulated kinases (ERKs), act as an integration
point for multiple biochemical signals, and are involved in a wide
variety of cellular processes such as proliferation, differentiation,
transcription regulation and development. The activation of this kinase
requires its phosphorylation by upstream kinases.
aptamer was selected by scientists at Base Pair Biotechnologies using
proprietary methods and ERK1 (aa 190-208) peptide CIADPEHDHTGFLTEYVATR
as a target.
***This aptamer does not bind phosphorylated aa202 pERK1 (aa 190-208) CIADPEHDHTGFL(t)EYVATR***
Target: ERK1 (aa190-208)
Target Species: human
Target Type: peptide
Dissociation Constant (Kd): 10.1 nM
Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.
*Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.
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