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Oligo Synthesis

Oligo Synthesis : Supports, CPGs

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3'-Amino-Modifier C7 CPG 1000

3'-Amino-Modifier C7 CPG 1000

Glen Research

Catalogue No.DescriptionPack SizePriceQty
20-2958-013'-Amino-Modifier C7 CPG 1000 0.1g £86.00 Quantity Add to Order
20-2958-103'-Amino-Modifier C7 CPG 1000 1.0g £614.00 Quantity Add to Order
20-2958-133'-Amino-Modifier C7 CPG 1000 1x10µm £227.00 Quantity Add to Order
20-2958-143'-Amino-Modifier C7 CPG 1000 1x15µm £341.00 Quantity Add to Order
20-2958-413'-Amino-Modifier C7 CPG 1000 4x1.0µm £127.00 Quantity Add to Order
20-2958-423'-Amino-Modifier C7 CPG 1000 4x0.2µm £77.00 Quantity Add to Order


3'-Amino-Modifier C7 CPG 1000


Catalog Number: 20-2958-xx

Description: 3'-Amino-Modifier C7 CPG 1000

1-succinoyl)-long chain alkylamino-CPG

F.W.: 209.18

Diluent: Not Applicable
Coupling: This support should be used in a manner identical to normal protected nucleoside support since it contains the DMT group.
Deprotection: Cleavage of the oligonucleotide from this support requires 2 hours at room temperature with ammonium hydroxide. Complete the deprotection using the protocol required by the nucleobases.
Storage: Freezer storage, -10 to -30°C, dry
Stability in Solution: Not Applicable


3’-Amino-Modifier CPGs, containing amino groups protected with the base-labile Fmoc group, are designed to functionalize the 3’-terminus of the target oligonucleotide by the introduction of a primary amine. In an alternative approach, the nitrogen destined to become the 3’-amino group is included in a phthalimide (PT) group which is attached to the support through an amide group attached to the aromatic ring. This simple linkage is very stable to all conditions of oligonucleotide synthesis and contains no chiral center. Using an extended ammonium hydroxide treatment (55°C for 17 hours), the cleavage of the amine from the phthalimide is accomplished along with the deprotection of the oligonucleotide. ABI-style columns are supplied unless otherwise requested.

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