| Conjugation Reagent (TCEP) |
Catalog Number: 50-1003-xx
Description: Conjugation Reagent (TCEP)
Diluent: Anhydrous Acetonitrile |
| Coupling: n/a |
| Deprotection: n/a |
| Storage: Refrigerated storage, maximum of 2-8°C, dry |
| Stability in Solution: 2-3 days |
| Please Note: OPeC™ reagents for research use are licensed under Patent No. PCT/GB00/03306 from the Medical Research Council, London, UK. These reagents are for research use only. A license for the commercial use of these products must be obtained from the Medical Research Council Technology, 20 Park Crescent, London W1N 4AL, UK. |
TERMINUS MODIFIERS
Glen Research 5’-Modifiers are designed for use in DNA synthesizers to functionalize the 5’-terminus of the target oligonucleotide. The 5’-Amino-Modifiers are available with a variety of chain lengths to fit exactly the desired application.
The DMS(O)MT-protected amino group is easier to deprotect compared to the MMT-protected one. The sulfoxy derivative survives conditions of oligonucleotide synthesis and can either be cleaved with standard deblock solution, or left intact for HPLC purification. At the same time, the DMS(O)MT group is fully compatible with cartridge purification. When detritylation on a cartridge is carried out, the DMS(O)MT , which is more stable than MMT , does not reattach itself to an amine. We now offer 5’-DMS(O)MT-Amino-Modifier C6 utilizing this new trityl based protecting group.
5’-Amino-Modifier TEG, a hydrophilic triethylene glycol ethylamine derivative, is 12 atoms in length and fully soluble in aqueous media.
If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200