Cambio - Excellence in Molecular Biology

Membrane protein work

Membrane protein work: Ultrapure Detergents

consumables for the solubilization and purification of membrane and soluble proteins.

Careful choice of detergents is maybe the most crucial factor when handling membrane proteins. Membrane proteins are in contact with lipidic membranes via large hydrophobic regions. Their extraction requires the use of detergents which possibly interfere with membrane protein structure and function. Different detergents can be optimal for extraction, purification, and crystallization steps.