Cambio - Excellence in Molecular Biology

Oligo Synthesis

Oligo Synthesis : Supports,CPGs

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Puromycin-CPG

Puromycin-CPG

Glen Research

Catalogue No.DescriptionPack SizePriceQty
20-4040-01Puromycin-CPG 0.1g £96.00£88.32Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-4040-10Puromycin-CPG 1.0g £796.00£732.32Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-4140-13Puromycin-CPG 1x10µm £288.00£264.96Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-4140-14Puromycin-CPG 1x15µm £432.00£397.44Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-4140-41Puromycin-CPG 4x1.0µm £160.00£147.20Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-4140-42Puromycin-CPG 4x0.2µm £96.00£88.32Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order

Puromycin-CPG

Puromycin-CPG

Glen Research

Puromycin-CPG

Structure

Catalog Number: 20-4040-xx

(20-4140-xx)

Description: Puromycin-CPG

5'-Dimethoxytrityl-N-trifluoroacetyl-puromycin,2'-succinoyl-long chain alkylamino-CPG


F.W.: 533.48

Diluent: Not Applicable
Coupling: This support should be used in a manner identical to normal protected nucleoside support since it contains the DMT group.
Deprotection: Deprotect using ammonium hydroxide and the protocol required by the nucleobases.
Storage: Controlled room temperature or lower, dry
Stability in Solution: Not Applicable

PUROMYCIN CPG

One of the most challenging requirements associated with combinatorial chemistry is the recovery of sequence information of the oligonucleotide or peptide selected by the screening assay. A method1 has been developed to generate a fusion product between mRNA and the polypeptide it encodes using in vitro translation of synthetic RNAs 3’-labeled with puromycin, an antibiotic that mimics transfer RNA. Puromycin binds in the ribosome’s A site, forms a peptide bond with the growing peptide chain, and blocks further peptide elongation. By linking puromycin to mRNA, a peptide-RNA fusion product results from the translation of the message linking the encoding mRNA with its peptide product.

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Puromycin-CPG

Puromycin-CPG

Glen Research

Material Safety Data Sheet

Glen Report 11.1: THE USE OF PUROMYCIN CPG IN COMBINATORIAL CHEMISTRY


If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200