Cambio - Excellence in Molecular Biology

Aptamers

Aptamers: Catalogue Aptamers

Please remember to pick your Modification from "Related items"

If the listed modifications do not meet your needs many other modifications are available on request

All Aptamers from Base Pair Bio are available with the following modifications

Please choose your modification and add as an extra catalogue number:

 

ATWUNMOD - Unmodified

ATWAMINE - Amine modification

ATWBIOTIN - Biotin modification

ATWTHIOL - Thiol modification (extra charge)

ATWFLUOR - Fluor (all) modification (extra charge)

 

BNP

Brain Natriuretic Peptide ATW0079

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
ATW0079-100BNP10 AEU (100ug) POA Quantity Add to Order
ATW0079-25BNP2.5 AEU (25ug) POA Quantity Add to Order

BNP

Brain Natriuretic Peptide ATW0079

Base Pair Bio

Brain natriuretic peptide, BNP-32, is a 32-amino acid peptide that is synthisized within the ventricles of the heart. Natriuretiuc peptides regulate sodium and water balance, blood volume, and arterial pressure. BNP-32 is a biomarker for heart failure.

DataSheet

Target:   BNP (Brain Natriuretic Peptide)

Target Species:   human

Target Type:   peptide

Affinity Constant (Kd):   61.3 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

Aptamer was selected at Base Pair Biotechnologies from a randomized 32-mer DNA library against the target protein.

 

Proprietary methods were then used to select the aptamer.

 

Aptamer folding instruction before use:

 

Once the aptamer is in its working concentration, it needs to be heated to 85-95 ºC for 5 minutes, and then cooled to room

 

temperature (~15 minutes) before use.

 

Validation data by Microscale Thernophoresis (MST) analysis:

 

Buffer used for validation: 1X PBS, pH = 7.4, 1 mM MgCl2, 0.05% Tween

Average Kd: 61.3 ± 9.9 nM

 

Please choose your modification and add as an extra catalogue number:

ATWUNMOD - Unmodified

ATWAMINE - Amine modification

ATWBIOTIN - Biotin modification

ATWTHIOL - Thiol modification (extra charge)

ATWFLUOR - Fluor (all) modification (extra charge)

 

Custom aptamers can be developed; contact us for details

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

BNP

Brain Natriuretic Peptide ATW0079

Base Pair Bio

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200