Cambio - Excellence in Molecular Biology

Cell Culture Contamination Control

Cell Culture Contamination Control: Prevention

Mycoplasma Prevention


Preventing mycoplasma contamination in lab work areas, safety cabinets and incubators as a routine cleaning measure can save time, money and the reputation of your lab. Timely decontamination of infected cell culture materials can also prevent further spreading of mycoplasma within your cell culture lab and can help avoid contamination of other cell lines.

Minerva Biolabs offer solutions for removal of mycoplasma from surfaces, equipment and from cell cultures themselves.

Mycoplasma elimination from surfaces and equipment


Mycoplasma Off® can be used for cleaning and disinfecting all kinds of laboratory surfaces and devices, including safety cabinets, incubators, work benches, sample storage boxes, and liquid nitrogen containers. Being rapidly effective against mycoplasma contamination, Mycoplasma Off® also has a broad antimicrobial activity against several other contaminants.  Available as wipes and sprays for convenience. Simply wipe or spray the surface for almost instant removal of mycoplasma.

1. - Convenient and Rapid

2. - Non-corrosive and Non-carcinogenic

3. - Broad Spectrum of Antimicrobial Activity

4. - Available as a spray (with refills) and handy wipes

 

 

Zellshield™

Zellshield™ protects cell cultures from a broad range of common contaminants and protects against most intracellular and extracellular growing gram negative and gram positive bacteria, mycoplasma, protozoon, fungi and yeast

Minerva Biolabs

Catalogue No.DescriptionPack SizePriceQty
13-0050Zellshield™24 tests £85.00 Quantity Add to Order
13-0150Zellshield™3 x 24 tests £226.00 Quantity Add to Order

Description

The Cell Culture Contamination Preventive 

Zellshield™ protects cell cultures from a broad range of common contaminants. The extremely powerful combination of innovative antibiotics is blocking the bacterial DNA synthesis, the protein biosynthesis or shows macrolidic properties. These bactericidal features allow the permanent removal of the contaminants from the culture. The use of old fashioned antibiotics like penicillin/streptomycin, nystatin or amphotericin B is not longer required! The easy applicable 100x aqueous solution is sterile filtrated and ready-to-go.

Format

Zellshield™ is shipped at room temperature and should be stored in the dark below -18°C.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

References

Bennett T.A. et al., (2014). Pharmacological profiles of acute myeloid leukemia treatments in patient samples by automated flow cytometry: a bridge to individualized medicine. Clinical Lymphoma, Myeloma & Leukemia, 14(4):305-18. doi: 10.1016/j.clml.2013.11.006.

Cagno V. et al., (2017). In vitro anti-herpes simplex virus-2 activity of Salvia desoleana Atzei & V. Picci essential oil. PLoS One, 12(2):e0172322. doi: 10.1371/journal.pone.0172322.

Carnesecchi J. et al., (2015). Estrogens Induce Rapid Cytoskeleton Re-Organization in Human Dermal Fibroblasts via the Non-Classical Receptor GPR30. PLoS One, 10(3):e0120672. doi: 10.1371/journal.pone.0120672.

 

Cavalli R. et al., (2011). Poly(amidoamine)-Cholesterol Conjugate Nanoparticles Obtained by Electrospraying as Novel Tamoxifen Delivery System. Journal of Drug Delivery, 2011:587604. doi: 10.1155/2011/587604.

 

Civra A. et al., (2015). Identification of Equine Lactadherin-Derived Peptides that Inhibit Rotavirus Infection via Integrin Receptor Competition. Journal of Biological Chemistry, 290(19):12403-14. doi: 10.1074/jbc.M114.620500.

 

Civra A. et al., (2017). In vitro screening for antiviral activity of Turkish plants revealing methanolic extract of Rindera lanata var. lanata active against human rotavirus. BMC Comlementary and Alternative Medicine, 17(1):74. doi: 10.1186/s12906-017-1560-3.

 

Corotchi M.C. et al., (2016). Testosterone stimulates proliferation and preserves stemness of human adult mesenchymal stem cells and endothelial progenitor cells. Romanian Journal of Morphology and Embryology, 57(1):75-80.

 

Jia J. et al., (2015). Caspases shutdown nonsense-mediated mRNA decay during apoptosis. Cell Death and Differentiation, 22(11):1754-63. doi: 10.1038/cdd.2015.18.

 

LaMarche M.J. et al., (2012). Anti-Hepatitis C Virus Activity and Toxicity of Type III Phosphatidylinositol-4-Kinase Beta Inhibitors. Antimicrobial Agents and Chemotherapy, 56(10):5149-56. doi: 10.1128/AAC.00946-12.

 

Latteyer S. et al., (2016). A 6-base pair in frame germline deletion in exon 7 of RET leads to increased RET phosphorylation, ERK activation, and MEN2A. Journal of Clinical Endocrinology and Metabolism 101(3):1016-22. doi: 10.1210/jc.2015-2948.

 

Pierzchalska M. et al., (2012). Prostaglandin E2 supports growth of chicken embryo intestinal organoids in Matrigel matrix. Biotechniques, 52(5):307-15. doi: 10.2144/0000113851.

 

Schmidt M. et al., (2015). Controlling the Balance of Fibroblast Proliferation and Differentiation: Impact of Thy-1. The Journal of Investigative Dermatology, 135(7):1893-902. doi: 10.1038/jid.2015.86.

 

Suzuki M. et al., (2016). Two isoforms of aquaporin 2 responsive to hypertonic stress in the bottlenose dolphin. Journal of Experimental Biology, 219(Pt 8):1249-58. doi: 10.1242/jeb.132811.

 

 

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Applications & Benefits

Application

  • For the  protection of cell cultures from a broad range of common contaminants

Benefits of Zellshield™ 

    • Broad Applicability - Zell Shield™ can be used for permanent cell cultures as well as for the protection of freshly prepared primary cells. 
    • No cell toxicity - Up to date, no cytotoxic effect on various cell lines treated has been reported if used as described. 
    • Specific - Zellshield™ is active against most intracellular and extracellular growing gram negative and gram positive bacteria, mycoplasma, protozoon, fungi and yeast. 
    • Easy to use - Simply add Zellshield™ directly to a freshly prepared cell culture or the premixed cell medium. 
    • Stability - The reagent is stable and active during typical incubation periods and conditions. 
    • Low Resistance Risk - The well selected antimicrobials show an extremely low resistance bias. Their combined activity reduces the probability for the survival of resistant mutants.

 

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Technical Help

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200