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Oligo Synthesis

Oligo Synthesis : Supports,CPGs

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3'-Glyceryl CPG

3'-Glyceryl CPG

Glen Research

Catalogue No.DescriptionPack SizePriceQty
20-2902-013'-Glyceryl CPG 0.1g £68.00£62.56Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-2902-103'-Glyceryl CPG 1.0g £480.00£441.60Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-2902-133'-Glyceryl CPG 1x10µm £180.00£165.60Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-2902-143'-Glyceryl CPG 1x15µm £280.00£257.60Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-2902-413'-Glyceryl CPG 4x1.0µm £100.00£92.00Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-2902-423'-Glyceryl CPG 4x0.2µm £60.00£55.20Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order

3'-Glyceryl CPG

3'-Glyceryl CPG

Glen Research

3'-Glyceryl CPG

Structure

Catalog Number: 20-2902-xx

Description: 3'-Glyceryl CPG

3-[(4,4'-Dimethoxytrityoxy)glyceryl-1-succinoyl]-
long chain alkylamino-CPG


F.W.: 154.06

Diluent: Not Applicable
Coupling: This support should be used in a manner identical to normal protected nucleoside support since it contains the DMT group.
Deprotection: Cleavage of the oligonucleotide from this support requires 2 hours at room temperature with ammonium hydroxide. Complete the deprotection using the protocol required by the nucleobases. Technical Bulletin
Storage: Freezer storage, -10 to -30°C, dry

Stability in Solution: Not Applicable

The 3’-Thiol-Modifier S-S CPG supports are used to introduce 3’-thiol linkages with three and six carbon spacers in oligonucleotides. DTPA CPG is used to introduce a dithiol group at the 3’-terminus. In conjunction with DTPA Phosphoramidite, it is simple to produce oligonucleotides with multiple thiol groups at the 3’ terminus, which is ideal for conjugation to gold surfaces. With Glyceryl CPG the 3’-terminus of an oligonucleotide is readily oxidized by sodium periodate to form a 3’-phosphoglycaldehyde. The aldehyde may be further oxidized to the corresponding carboxylic acid. Either the aldehyde or the carboxylate may be used for subsequent conjugation to amine-containing products.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

3'-Glyceryl CPG

3'-Glyceryl CPG

Glen Research

MSDS

Glen Report 7.1

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200