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Oligo Synthesis

Oligo Synthesis : Supports,CPGs

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DesthiobiotinTEG-CPG

DesthiobiotinTEG-CPG

Glen Research

Catalogue No.DescriptionPack SizePriceQty
20-2952-01DesthiobiotinTEG-CPG 0.1g £112.00£103.04Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-2952-10DesthiobiotinTEG-CPG 1.0g £920.00£846.40Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-2952-13DesthiobiotinTEG-CPG 1x10µm £276.00£253.92Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-2952-14DesthiobiotinTEG-CPG 1x15µm £416.00£382.72Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-2952-41DesthiobiotinTEG-CPG 4x1.0µm £184.00£169.28Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order
20-2952-42DesthiobiotinTEG-CPG 4x0.2µm £112.00£103.04Offer until : 31-Dec-2019Offer Code : GLEN88% off all Glen Research products View Offer Quantity Add to Order

DesthiobiotinTEG-CPG

DesthiobiotinTEG-CPG

Glen Research

DesthiobiotinTEG-CPG

Structure

Catalog Number: 20-2952-xx

Description: DesthiobiotinTEG-CPG

1-Dimethoxytrityloxy-3-O-(N-desthiolbiotinyl-3-aminopropyl)-triethyleneglycolyl-
glyceryl-2-O-succinyl-long chain alkylamino-CPG


F.W.: 539.56

Diluent: Anhydrous Acetonitrile
Coupling: This support should be used in a manner identical to normal protected nucleoside support since it contains the DMT group.
Deprotection: Deprotect using the protocol required by the nucleobases.
Storage: Freezer storage, -10 to -30°C, dry
Stability in Solution: 2-3 days

Biotin-dT can replace dT residues within the oligonucleotide sequence. 5’-Biotin phosphoramidite can be added ONLY ONCE to the 5’-terminus of an oligonucleotide. However, the DMT group on the biotin can be used in RP cartridge and HPLC purification techniques. PC Biotin is a photocleavable 5’-biotin phosphoramidite. BiotinTEG CPG and Protected BiotinLC Serinol CPG are designed for the direct synthesis of oligonucleotides containing biotin at the 3’ terminus.

Desthiobiotin is a biotin analogue that exhibits lower binding to biotin-binding proteins such as streptavidin. This biotin analogue is lacking the sulfur group from the molecule and has a dissociation constant (Kd) several orders of magnitude less than biotin/streptavidin. As a result, biomolecules containing desthiobiotin are dissociated from streptavidin simply in the presence of buffered solutions of biotin. We offer desthiobiotinTEG phosphoramidite and the corresponding CPG.

ABI-style vials and columns are supplied unless otherwise requested.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

DesthiobiotinTEG-CPG

DesthiobiotinTEG-CPG

Glen Research

MSDS

Glen Report 16.2: STILL MORE NEW PRODUCTS

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200