| 3'-PT-Amino-Modifier C6 PS |
Catalog Number: 26-2956-xx
Description: 3'-PT-Amino-Modifier C6 PS
| N-(6-(O-Dimethoxytrityl)-hexyl)-(2-carboxamide)-phthalimidyl-polystyrene |
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F.W.: 179.15 |
Diluent: Anhydrous Acetonitrile |
| Coupling: This support should be used in a manner identical to normal protected nucleoside support since it contains the DMT group. |
| Deprotection: Cleavage of the oligonucleotide from this support requires overnight at 55°C with ammonium hydroxide or AMA for 10 minutes at 65°C. This treatment will complete the deprotection of the nucleobases. For a complete list of cleavage conditions, see www.glenres.com/GlenReports/GR15-12.html. |
| Storage: Freezer storage, -10 to -30°C, dry |
| Stability in Solution: 2-3 days |
AB 3900 Polystyrene Modifier Columns
Some of our more popular minor base and modifier supports are available on polystyrene in columns fully compatible with the Applied Biosystems 3900 synthesizer. These include our popular Universal Support III, which will allow DNA, RNA or LNA oligos to be produced on the 3900 with ANY base at the 3’ terminus. At the same time, we are offering 1 µmole columns of Universal Support III for the 3900 instrument. Structures and more complete descriptions are found in the relevant catalog sections for each item. AB 3900 columns can be prepared with virtually any of the CPG supports in this catalog. However, it is usually necessary to adjust the flow using CPG columns since CPG has different flow characteristics from polystyrene.
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