Cambio - Excellence in Molecular Biology

Aptamers

Aptamers: Catalogue Aptamers

Please remember to pick your Modification from "Related items"

If the listed modifications do not meet your needs many other modifications are available on request

All Aptamers from Base Pair Bio are available with the following modifications

Please choose your modification and add as an extra catalogue number:

 

ATWUNMOD - Unmodified

ATWAMINE - Amine modification

ATWBIOTIN - Biotin modification

ATWTHIOL - Thiol modification (extra charge)

ATWFLUOR - Fluor (all) modification (extra charge)

 

PBP-2a (MRSA) Aptamer to Bacterial Protein

PBP-2a (MRSA) Aptamer to Bacterial Protein ATW0033

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
ATW0033-100PBP-2a (MRSA) 10 AEU (100ug) POA Quantity Add to Order
ATW0033-25PBP-2a (MRSA) 2.5 AEU (25ug) POA Quantity Add to Order

PBP-2a (MRSA) Aptamer to Bacterial Protein

PBP-2a (MRSA) Aptamer to Bacterial Protein ATW0033

Base Pair Bio

Methicillin-resistant Staphylococcus aureus, abbreviated MRSA, is one of a number of greatly feared strains of S. aureus which have become resistant to most B lactam antibiotics. Resistance is conferred by the mecA gene, which codes for an altered penicillin-binding protein (PBP2a or PBP2') that has a lower affinity for binding B lactams (penicillins,cephalosporins, and carbapenems). This allows for resistance to all B lactam antibiotics, and obviates their clinical use during MRSA infections.

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and Recombinant Staphylococcus aureus PBP2a, [Ray Biotech Cat # 230-00051] as a target and 1X PBS, pH 7.4, 0.01% BSA, 0.002% Tween20.  Let us know if you have any questions about its development or potential uses.

Target:   PBP-2a, Penicillin-binding-protein 2a from Staphylococcus aureus

Target Species:   bacterial

Target Type:   protein

Affinity Constant (Kd):   23.5 nM

Aptamer information Kd 23.5 nM

MRSA ATW0033 #820 datasheet

Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

PBP-2a (MRSA) Aptamer to Bacterial Protein

PBP-2a (MRSA) Aptamer to Bacterial Protein ATW0033

Base Pair Bio

Antibody Equivalent Units (AEU).  There is a  large molecular weight difference in antibodies (typically 150,000 Da) and Base Pair’s aptamers (~14,000 Da).   We provide our aptamers in terms of moles, where the aptamer moles in 1  AEU is equal to antibody moles in the typical 100 microgram shipment from a leading antibody vendor. Therefore our standard 2.5 AEU (25ug) or 5 AEU (50ug) delivery is 2.5 and 5 times the equivalent moles of a standard antibody delivery of 100 microgram respectively

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200