Cambio - Excellence in Molecular Biology

Aptamers

Aptamers: Catalogue Aptamers

Please remember to pick your Modification from "Related items"

If the listed modifications do not meet your needs many other modifications are available on request

All Aptamers from Base Pair Bio are available with the following modifications

Please choose your modification and add as an extra catalogue number:

 

ATWUNMOD - Unmodified

ATWAMINE - Amine modification

ATWBIOTIN - Biotin modification

ATWTHIOL - Thiol modification (extra charge)

ATWFLUOR - Fluor (all) modification (extra charge)

 

Latency Associated Peptide (LAP) (hu)

Latency Associated Peptide (LAP) Aptamer ATW0026

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
ATW0026-100Latency Associated Peptide (LAP) (hu) 10 AEU (100ug) POA Quantity Add to Order
ATW0026-25Latency Associated Peptide (LAP) (hu) 2.5 AEU (25ug) POA Quantity Add to Order

Latency Associated Peptide (LAP) (hu)

Latency Associated Peptide (LAP) Aptamer ATW0026

Base Pair Bio

TGF-beta is secreted by many cell types, including macrophages, in a latent form in which it is complexed with two other polypeptides, latent TGF-beta binding protein (LTBP) and? latency associated peptide (LAP). Serum proteinases such as plasmin catalyze the release of active TGF-beta from the complex. This often occurs on the surface of macrophages where the latent TGF-beta complex is bound to CD36 via its ligand, thrombospondin-1 (TSP-1). This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and recombinant? Latency Associated Peptide (LAP), [R&D Systems, Cat# 246-LP/CF]? as a target.

Target:   LAP / TGF beta 1 Complex (Latency Associated Peptide, Transforming Growth Factor Beta 1)

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   17.5 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

Datasheet

0.1uM synthesis scale (20-200ug)
Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

Latency Associated Peptide (LAP) (hu)

Latency Associated Peptide (LAP) Aptamer ATW0026

Base Pair Bio

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200