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Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

Human Chloride Intracellular Channel 1 (CLIC1)

Human Chloride Intracellular Channel 1 (CLIC1)

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
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ATW0046-100Human Chloride Intracellular Channel 1 (CLIC1) 10 AEU (100ug) POA Quantity Add to Order
ATW0046-25Human Chloride Intracellular Channel 1 (CLIC1) 2.5 AEU (25ug) POA Quantity Add to Order

Description

Chloride intracellular channel protein 1, CLIC1, is found primarily in the nucleus and nuclear membrane. It can insert into membranes to form chloride ion channels. Membrane insertion is redox-dependent (occurring under oxidizing conditions) and channel activity is pH-dependent. CLIC-1 is involved in the regulation of cell cycle.

Target:   CLIC1 (Chloride Intracellular Channel 1)

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   42.7 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

Aptamer was selected from a randomized 32-mer library against Human CLIC 1 protein. Proprietary methods were then used to select the aptamer.

DataSheet

0.1uM synthesis scale (20-200ug)
Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)

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Protocols

DataSheet

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References

www.uniprot.org/uniprot/O00299

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Notes

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

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Related products

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