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Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

Zika aptamer ATW0105

This Zika aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and Zika envelope protein from ProSpec as a target.

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
  • Change to:
  • £
ATW0105-100ATW0105 Zika Aptamer10 AEU (100ug) POA Quantity Add to Order
ATW0105-25ATW0105 Zika Aptamer2.5 AEU (25ug) POA Quantity Add to Order

Description

Zika virus is a mosquito-borne flavivirus. It is transmitted by the Aedes mosquito, which also transmits Dengue, Chikungunya, and yellow fever. Contraction of Zika during pregnancy can cause microcephaly and other abnormalities in newborns as well as fetal loss, stillbirth, and pre-term birth. Zika infection has also been linked to Guillain-Barre syndrome, neuropathy, and myelitis (1). This DNA aptamer was selected against the Zika envelope protein in mosquito saliva, but has also been shown to bind the Zika envelope protein in serum and defibrinated blood (2).

  1. WHO. https://www.who.int/news-room/fact-sheets/detail/zika-virus. Accessed May 15, 2019.
  2. Saraf, N., et al. Multiplex viral detection platform based on a aptamers-integrated microfluidic channel. ACS Omega. 2019. 4:2234-2240.

Target:   Zika

Target Species:   viral

Target Type:   protein

Affinity Constant (Kd):   8.8 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.


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Protocols

Download protocol from Base Pair's website here https://www.basepairbio.com/store/atw0105-zika-aptamer/

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References

1. WHO. https://www.who.int/news-room/fact-sheets/detail/zika-virus. Accessed May 15, 2019. 2. Saraf, N., et al. Multiplex viral detection platform based on a aptamers-integrated microfluidic channel. ACS Omega. 2019. 4:2234-2240.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Notes

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Related products

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200