Cambio - Excellence in Molecular Biology

Aptamers

Aptamers: Catalogue Aptamers

Please remember to pick your Modification from "Related items"

If the listed modifications do not meet your needs many other modifications are available on request

All Aptamers from Base Pair Bio are available with the following modifications

Please choose your modification and add as an extra catalogue number:

 

ATWUNMOD - Unmodified

ATWAMINE - Amine modification

ATWBIOTIN - Biotin modification

ATWTHIOL - Thiol modification (extra charge)

ATWFLUOR - Fluor (all) modification (extra charge)

 

Dengue Type 2 NS1 Viral Protein Aptamer

Dengue virus type 2 NS1 BRCAX Viral Protein Aptamer ATW0064

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
ATW0064-100Dengue NS1 protein 10 AEU (100ug) POA Quantity Add to Order
ATW0064-25Dengue NS1 protein 2.5 AEU (25ug) POA Quantity Add to Order

Dengue Type 2 NS1 Viral Protein Aptamer

Dengue virus type 2 NS1 BRCAX Viral Protein Aptamer ATW0064

Base Pair Bio

According to the CDC, 50 to 100 milllion people, primarily in the tropics, are infected with dengue virus each year. There are approximately 500,000 cases of dengue hemorrhagic fever, and 22,000 deaths. There are no vaccines against dengue and no treatment for infection. The NS1 protein is detectable in human serum of infected individuals. It is a 50 kDa non-structural glycoprotein that interacts with intracellular membranes and the cell surface. The NS1 protein appears to utilize normal lipid metabolic pathways to affect the complement system and promote infection.

Target:   Dengue Type 2 NS1 (non-structural protein)

Target Species:   viral

Target Type:   protein

Affinity Constant (Kd):   6.8 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

Aptamer was selected at Base Pair Biotechnologies from a randomized 32-mer DNA library against recombinant Dengue virus type 2 NS1 protein. Proprietary methods were then used to select the aptamer.

Datasheet

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Dengue Type 2 NS1 Viral Protein Aptamer

Dengue virus type 2 NS1 BRCAX Viral Protein Aptamer ATW0064

Base Pair Bio

Gutsche, I. et al. (2011) Secreted dengue virus nonstructural protein NS1 is an atypical barrel-shaped high-density lipoprotein. PNAS. 108(19):8003-08.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

Dengue Type 2 NS1 Viral Protein Aptamer

Dengue virus type 2 NS1 BRCAX Viral Protein Aptamer ATW0064

Base Pair Bio

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200